Edisto Island, SC is a city located in Colleton County, South Carolina and has a land area of 75.12 square miles (194.56 km2). The water area for the city is 18.40 square miles or 47.66 km2. There is one unique zip code in Edisto Island, South Carolina and it is 29438. The area code(s) for Edisto Island is 843/854.
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